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Home >> Antibodies >> CD57 / B3GAT1 (Natural Killer Cell Marker)

CD57 / B3GAT1 (Natural Killer Cell Marker)

Mouse Monoclonal Antibody [Clone NK-1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Formalin-fixed, paraffin-embedded human Spleen stained with CD57 Monoclonal Antibody (NK-1).

Product Details

Synonyms

3-Glucuronyltransferase 1; B3GAT1; Galactosylgalactosylxylosylprotein 3-beta-Glucuronosyltransferase 1; GLCATP; GlcUAT-P; Glucuronosyltransferase P; UDP GlcUA Glycoprotein beta 1, 3 Glucuronyltransferase

Positive Control

Lymph node or Tonsil.

Known Applications & Suggested Dilutions

IF, IHC-P         More Details

Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Membrane antigen from HSB-2 cells

Cellular Localization

Cell surface

Species Reactivity

Human. Does not react with Rat.

Host / Ig Isotype

Mouse / IgM, kappa

Mol. Weight of Antigen

~110kDa (Glycoprotein)

Specificity & Comments

Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Abo T et. al. J Immunol, 1982, 129(4):1758-61.
  2. Lanier, LL et al. J. Immunology 131:1789 (1983).
  3. Abo T et al. J Immunology, 1982, 129:1752-7.
  4. McGarry, RC et al. Nature 306:376 (1983).

Bioinformatics

  •  Entrez Gene ID: 27087
  •  Gene Symbol: B3GAT1
  •  SwissProt: Q9P2W7
  •  Chromosome Location: 11q25
  •  Unigene: 381050
NBT00016