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Home >> Antibodies >> CD51 / Integrin V

CD51 / Integrin V

Mouse Monoclonal Antibody [Clone ITGAV/1610]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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SDS-PAGE Analysis Purified CD51 / Integrin 'V Mouse Monoclonal Antibody (ITGAV/1610). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

antigen identified by monoclonal antibody L230; CD 51; CD51; DKFZp686A08142; Integrin alpha five; integrin alpha V beta 3; Integrin alpha-5; integrin alpha-V; Integrin alpha-V light chain; integrin alphaVbeta3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITAV_HUMAN; ITGAV; MSK 8; Msk8; Vitronectin receptor subunit alpha; VNRA; VTNR

Positive Control

Squamous cells, A375M melanoma cells. A549 cells.

Known Applications & Suggested Dilutions

ELISA, Flow Cyt, IF, Western Blot         More Details

ELISA (For coating use Ab at 1-5ug/ml, order Ab without BSA)
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human full-length integrin alpha V beta 1 protein

Cellular Localization

Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

150-160kDa under non-reducing conditions. Under reducing conditions, it is cleaved into 2 bands of about 125-130kDa +20-25kDa.

Specificity & Comments

Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Nilsson, M., et al. 2004. J. Gene Med. 6: 631-641.

Bioinformatics

  •  Entrez Gene ID: 3685
  •  Gene Symbol: ITGAV
  •  SwissProt: P06756
  •  Chromosome Location: 2q32.1
  •  Unigene: 436873
NBT01610