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Home >> Antibodies >> CD48 (Pan Leukocyte Marker)

CD48 (Pan Leukocyte Marker)

Mouse Monoclonal Antibody [Clone 156-4H9]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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SDS-PAGE Analysis Purified CD48 Mouse Monoclonal Antibody (156-4H9). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

B-cell activation marker; B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; BLAST1; CD48 antigen (B cell membrane protein); Signaling lymphocytic activation molecule 2 (SLAMF2); SLAM family member 2

Positive Control

Daudi, JY, Raji, Jurkat and human lymphocytes. Human lymph node and tonsil.

Known Applications & Suggested Dilutions

Func., Flow Cyt, IF         More Details

Functional Studies (Order Ab without Azide)
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Human CD48 protein

Cellular Localization

Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

45kDa

Specificity & Comments

Reacts with human CD48, a 45kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Yokoyama S et al. Expression of the Blast-1 activation/adhesion molecule and its identification as CD48. J Immunol 1991, 146(7):2192-2200.
  2. Kishimoto T. et al., eds. Leukocyte Typing VI, p509-514, Garland Publishing, Inc, New York and London, 1997.
  3. Kwong YL et al. Flow cytometric measurement of glycosylphosphatidyl-inositol-linked surface proteins on blood cells of patients with paroxysmal nocturnal hemoglobinuria. Am J Clin Pathol 1994, 102(1):30-35

Bioinformatics

  •  Entrez Gene ID: 962
  •  Gene Symbol: CD48
  •  SwissProt: P09326
  •  Chromosome Location: 1q21.3-q22
  •  Unigene: 243564
NBT00307