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Catalog No
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Product Details
Synonyms
Positive Control
Known Applications & Suggested Dilutions
Immunogen
Cellular Localization
Species Reactivity
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90kDa and 140kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/ 3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.
Key References