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Home >> Antibodies >> CD357 / GITR

CD357 / GITR

Mouse Monoclonal Antibody [Clone GITR/1585]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00

Product Details

Synonyms

Activation inducible TNFR family receptor; AITR; GITRD; Glucocorticoid induced TNFR related protein; Glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation inducible protein; TNFRSF18

Positive Control

Jurkat cells.

Known Applications & Suggested Dilutions

ELISA         More Details

ELISA (For coating, order Ab without BSA & Azide)
Optimal dilution for a specific application should be determined.

Immunogen

Human full-length TNFRSF18 protein

Cellular Localization

Secreted and Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG3, kappa

Mol. Weight of Antigen

25kDa

Specificity & Comments

The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals through protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Gruss, H.J. 1996. Int. J. Clin. Lab. Res. 26: 143-159.

Bioinformatics

  •  Entrez Gene ID: 8784
  •  Gene Symbol: TNFRSF18
  •  SwissProt: Q9Y5U5
  •  Chromosome Location: 1p36.33
  •  Unigene: 212680
NBT01585