Formalin-fixed, paraffin-embedded human Tonsil stained with CD27 Recombinant Mouse Monoclonal Antibody (rLPFS2/1611).
SDS-PAGE Analysis Purified CD27 Recombinant Mouse Monoclonal Antibody (rLPFS2/1611). Confirmation of Integrity and Purity of Antibody.
Flow Cytometric Analysis of Ramos cells using CD27 Recombinant Mouse Monoclonal Antibody (rLPFS2/1611) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.