2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> CD26 (DPP IV / ADA-Binding Protein)

CD26 (DPP IV / ADA-Binding Protein)

Mouse Monoclonal Antibody [Clone 202.36]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00

Product Details

Synonyms

ADA-binding protein (ADABP); Adenosine deaminase complexing protein 2 (ADCP-2); Dipeptidyl peptidase 4; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; Dipeptidyl peptidase, intestinal; Dipeptidylpeptidase 4; Dipeptidylpeptidase IV; DPP4; DPPIV; Intestinal dipeptidyl peptidase; T-cell activation antigen CD26; TP103

Positive Control

YT, HEP-G2 cells and lymphocytes. Lymph nodes and tonsils.

Known Applications & Suggested Dilutions

Flow Cyt, IF, IHC         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Frozen Only) (1-2ug/ml for 30 minutes at RT) Optimal dilution for a specific application should be determined.

Immunogen

Human T cell clone

Cellular Localization

Cell Surface

Species Reactivity

Human. Rat. Does not react with Pig or Sheep.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

110kDa

Specificity & Comments

Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Kishimoto T. et al., eds. Leukocyte Typing VI, p478-489 and p1128, Garland Publishing, Inc, New York and London, 1997.

Bioinformatics

  •  Entrez Gene ID: 1803
  •  Gene Symbol: DPP4
  •  SwissProt: P27487
  •  Chromosome Location: 2q24.3
  •  Unigene: 368912
NBT00888