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Home >> Antibodies >> CD2 / Lymphocyte Function Antigen 2 (LFA-2)

CD2 / Lymphocyte Function Antigen 2 (LFA-2)

Mouse Monoclonal Antibody [Clone LFA2/7102]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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SDS-PAGE Analysis Purified CD2 Mouse Monoclonal Antibody (LFA2/7102). Confirmation of Purity and Integrity of Antibody.

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IHC analysis of formalin-fixed, paraffin-embedded human tonsil. Strong cell surface staining using LFA2/7102 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

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IHC analysis of formalin-fixed, paraffin-embedded human lymph node. Strong cell surface staining using LFA2/7102 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

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Formalin-fixed, paraffin-embedded human tonsil stained with CD2 Mouse Monoclonal Antibody (LFA2/7102) at 2ug/ml. Inset: PBS instead of primary antibody; secondary only negative control.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using CD2-Monospecific Mouse Monoclonal Antibody (LFA2/7102).

Product Details

Synonyms

Erythrocyte receptor; LFA-2; LFA-3 receptor; Ly-37; Lymphocyte function antigen 2; Rosette receptor; SRBC; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T11

Positive Control

Human tonsil, spleen or lymph node.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment of human CD2 protein (exact sequence is proprietary)

Cellular Localization

Cell surface.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

39kDa

Specificity & Comments

CD2 is mainly present on the surface of mature T cells and NK cell membranes, while B cells are usually not expressed. It can be used to label the diagnosis and study of normal T cells and their associated tumors, such as pre-t cell lymphoma, marginal T cell lymphoma and anaplastic cell lymphoma. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Companioni N poles O, et al. J Gastroenterol 52:39-49 (2017).
  2. DE Sanctis V, Belgioia L, et al. Anticancer Research 39:1935-1942 (2019).

Bioinformatics

  •  Entrez Gene ID: 914
  •  Gene Symbol: CD2
  •  SwissProt: P06729
  •  Chromosome Location: 1p13.1
  •  Unigene: 523500