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Home >> Antibodies >> CD15 / FUT4 (Reed-Sternberg Cell Marker)

CD15 / FUT4 (Reed-Sternberg Cell Marker)

Mouse Monoclonal Antibody [Clone FUT4/815 + BRA-4F1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Formalin-fixed, paraffin-embedded human Hodgkin's lymphoma stained with CD15 Mouse Monoclonal Antibody (FUT4/815 + BRA-4F1).

Product Details

Synonyms

3 Fucosyl N Acetyl Lactosamine; Alpha (1,3) Fucosyltransferase; Alpha 13 fucosyltransferase FucT; ELAM Ligand Fucosyltransferase; ELFT; FCT3A; Fuc-TIV; Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific; Fucosyltransferase 4; Galactoside 3 L Fucosyltransferase; Lewis X; LeX; SSEA1; Stage Specific Embryonic Antigen 1

Positive Control

U937 cells, Reed-Sternberg's cells in Hodgkin's lymphoma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Immunogen

Purified human neutrophils (FUT4/815); Myelomonocytic leukemia cells (BRA-4F1)

Cellular Localization

Cell surface and granular paranuclear

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgM, kappa

Mol. Weight of Antigen

~220kDa (Glycoprotein)

Specificity & Comments

CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Hsu et. al. Amer J Clin Pathol 82: 29, 1984.
  2. Pinkus et. al. Am J Pathol 119: 244, 1985.

Bioinformatics

  •  Entrez Gene ID: 2526
  •  Gene Symbol: FUT4
  •  SwissProt: P22083
  •  Chromosome Location: 11q21
  •  Unigene: 654379
NBT00562