2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> CD134, Mouse (OX40)

CD134, Mouse (OX40)

Rat Monoclonal Antibody [Clone OX-86]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
img

SDS-PAGE Analysis Purified CD134 Rat Monoclonal Antibody (OX-86). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

CD134; IMD16; Lymphoid activation antigen (ACT35); OX40 cell surface antigen; OX40L receptor; TAX transcriptionally activated glycoprotein 1 receptor; Tumor necrosis factor receptor superfamily member 4 (TNFRSF4); Txgp1l

Positive Control

MPBMC's. Spleen, Thymus or Lymph Node.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Does not block binding of OX40L
Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Purified recombinant Mouse OX-40 antigen

Cellular Localization

Cell Surface

Species Reactivity

Mouse. Does not react with Human.

Host / Ig Isotype

Rat / IgG1, kappa

Mol. Weight of Antigen

50kDa

Specificity & Comments

CD134 is a type I integral membrane protein. This receptor is expressed on activated CD4+and CD8+T cells and B cells. The CD134 binds to CD134 ligand (CD252) to provide a costimulatory signal that is independent of CD28. CD134 is involved in coordinating CD4 T cell selection, migration and cytokine differentiation in T helper (Th)1 and Th2 cells. CD134 is also involved in the stimulation of T cells, T dependent humoral response and generation of optimal CD4+ T cell responses in vivo and in vitro. CD134 is expressed on activated CD4+ T lymphocytes, and its ligand, CD134L, is found preferentially on activated B cells. Engagement of CD134 with its ligand, CD134L, delivers a strong costimulatory signal to effector T cells.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Higgins LM, et al. 1999. J. Immunol. 162:486. (Flow IHC)
  2. del Rio ML, et al. 2011. Transpl. Int. 24:501. (Flow)
  3. Al-Shamkhani A, et al. 1996. Eur. J. Immunol. 26:1695. (Agonist)

Bioinformatics

  •  Entrez Gene ID: 22163
  •  SwissProt: P47741
  •  Chromosome Location: 4 E2; 4 87.68 cM (Mouse)
  •  Unigene: 13885
NBT02004