Formalin-fixed, paraffin-embedded human Liver stained with Cathepsin K Mouse Monoclonal Antibody (CTSK/2793).
Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with Cathepsin K Mouse Monoclonal Antibody (CTSK/2793).
SDS-PAGE Analysis Purified Cathepsin K Mouse Monoclonal Antibody (CTSK/2793). Confirmation of Purity and Integrity of Antibody
Analysis of Protein Array containing more than 19,000 full-length human proteins using Cathepsin K Mouse Monoclonal Antibody (CTSK/2793)
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.