SDS-PAGE Analysis Purified Alpha-1-Antitrypsin Mouse Monoclonal (AAT/6325). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human tonsil stained with Alpha-1-Antitrypsin Mouse Monoclonal Antibody (AAT/6325). Inset: PBS instead of primary antibody; secondary only negative control.
Formalin-fixed, paraffin-embedded human liver in colon stained with Alpha-1-Antitrypsin Mouse Monoclonal (AAT/6325). HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Alpha-1-Antitrypsin Mouse Monoclonal (AAT/6325).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
It recognizes a protein of 54kDa, which is identified antitrypsin (AAT). The immunohistochemical staining of AAT is useful in identification of benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for AAT is also used in detection of benign and malignant lesions of histiocytic nature. This antibody is may also useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with fibrosis of uncertain origin.