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Home >> Antibodies >> ALDH1A1 (Aldehyde Dehydrogenase 1A1)

ALDH1A1 (Aldehyde Dehydrogenase 1A1)

Mouse Monoclonal Antibody [Clone ALDH1A1/1381]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).

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Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).

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Western Blot of K562 and Lung lysate ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).

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Western Blot Analysis of human Liver tissue lysate using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).

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SDS-PAGE Analysis Purified ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

Acetaldehyde dehydrogenase 1; AHD2; ALDC; Aldehyde dehydrogenase 1 soluble; Aldehyde dehydrogenase 1A1; Aldehyde dehydrogenase family 1 member A1; ALDH-E1; ALDH1; ALDH1A1; epididymis luminal protein 12; epididymis luminal protein 9; epididymis secretory sperm binding protein Li 53e; HEL-S-53e; PUMB1; RALDH1; Retinal dehydrogenase 1

Positive Control

Liver, K562, Lung, HepG2 or A549 cells. Colon or Testicular Carcinoma.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa 315-434) of human ALDH1A1 protein (exact sequence is proprietary).

Cellular Localization

Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

56kDa

Specificity & Comments

ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Xu J, Muller S., et al. Comparison of quantum dot technology with conventional immunohistochemistry in examining aldehyde dehydrogenase 1A1 as a potential biomarker for lymph node metastasis of head and neck cancer. Eur J Cancer. 2012 Jul;48(11):1682-91

Bioinformatics

  •  Entrez Gene ID: 216
  •  Gene Symbol: ALDH1A1
  •  SwissProt: P00352
  •  Chromosome Location: 9q21.13
  •  Unigene: 76392
NBT01381