|Catalog No||Formulation||Size||Price (USD)|
|199-MSM2-P0||Purified Ab with BSA and Azide at 200ug/ml||20 ug||199.00|
|199-MSM2-P1||Purified Ab with BSA and Azide at 200ug/ml||100 ug||429.00|
|199-MSM2-P1ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||100 ug||429.00|
|Human Entrez Gene ID||199|
|Human Gene Symbol||AIF1|
|Human Chromosome Location||6p21.33|
|Synonyms||Allograft inflammatory factor 1 (AIF1); balloon angioplasty responsive transcription (BART1); IBA1; Interferon responsive transcript 1; Ionized calcium-binding adapter molecule 1; IRT1; Microglia response factor (MRF1)|
|Immunogen||Purified recombinant human AIF1 protein (around aa 1-146) (exact sequence is proprietary)|
|Host / Ig Isotype||Mouse / IgG1, kappa|
|Mol. Weight of Antigen||17kDa|
|Cellular Localization||Cytoplasmic and Cell Surface|
|Species Reactivity||Human. Others not known.|
AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
Lymph Node, Tonsil or Kidney
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
This antibody is available for research use only and is not approved for use in diagnosis.
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.