|Catalog No||Formulation||Size||Price (USD)|
|9370-MSM3-P0||Purified Ab with BSA and Azide at 200ug/ml||20 ug||199.00|
|9370-MSM3-P1||Purified Ab with BSA and Azide at 200ug/ml||100 ug||379.00|
|9370-MSM3-P1ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||100 ug||399.00|
|Human Entrez Gene ID||9370 (Human)|
|Human SwissProt||Q15848 (Human)|
|Human Unigene||80485 (Human)|
|Human Gene Symbol||ADIPOQ|
|Human Chromosome Location||3q27|
|Synonyms||Adiponectin; Adipocyte complement-related 30kDa protein (ACRP30); Adipocyte-specific secretory protein; Adiponectin, C1Q and collagen domain containing (ACDC); ADIPOQ; Adipose most abundant gene transcript 1 protein; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM-1; Gelatin-binding protein 28 (GBP28)|
|Immunogen||Recombinant human Adiponectin protein fragment|
|Host / Ig Isotype||Mouse / IgG2b|
|Mol. Weight of Antigen||26-30kDa|
|Cellular Localization||Cytoplasmic & Cell Surface|
|Species Reactivity||Human. Others not known.|
This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.
ELISA (For coating, use antibody without BSA),Flow Cytometry (0.5-1ug/million cells)
Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
HeLa cells or Kidney
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
This antibody is available for research use only and is not approved for use in diagnosis.
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.